Vidya Mohamed-Ali
Peer-reviewed journals

  1. Marina N., Tang F., Figueiredo M., Mastitskaya S., Kasimov V., Mohamed-Ali V., Roloff E., Teschemacher A.G., Gourine A.V., Kasparov S. (2013). Purinergic signalling in the rostral ventro-lateral medulla controls sympathetic drive and contributes to the progression of heart failure following myocardial infarction in rats. Basic Res Cardiol. 108:317
  2. Kourliouros, A., Karastergiou, K., Nowell, J., Gukop, P., Tavakkoli Hosseini, M., Valencia, O., Mohamed Ali, V., Jahangiri, M. (2011). Protective effect of epicardial adiponectin on atrial fibrillation following cardiac surgery. Eur J Cardiothorac Surg 39(2), 228-232
  3. Flachs, P., Rühl, R., Hensler, M., Janovska, P., Zouhar, P., Kus, V., Macek Jilkova, Z., Papp, E., Kuda, O., Svobodova, M., Rossmeisl, M., Tsenov, G., Mohamed-Ali, V., Kopecky, J. (2011). Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids. Diabetologia 54(10), 2626-2638
  4. Speakman, J.R., Levitsky, D.A., Allison, D.B., Bray, M.S., de Castro, J.M., Clegg, D.J., Clapham, J.C., Dulloo, A.G., Gruer, L., Haw, S., Hebebrand, J., Hetherington, M.M., Higgs, S., Jebb, S.A., Loos, R.J.F., Luckman, S., Luke, A., Mohamed-Ali, V., O’Rahilly, S., Periera, M., Perusse, L., Robinson, T.N., Rolls, B., Symonds, M.E. and Westerterp-Plantenga, M.S. (2011). Set-points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity. Disease Models and Mechanisms. 4:733-745
  5. Karastergiou, K., Evans, I., Ogston, N., Miheisi, N., Nair, D., Kaski, J. C., Jahangiri, M., Mohamed-Ali, V. (2010). Epicardial adipokines in obesity and coronary artery disease induce atherogenic changes in monocytes and endothelial cells. Arterioscler Thromb Vasc Biol 30(7), 1340-1346
  6. Karastergiou, K., Mohamed-Ali, V. (2010). The autocrine and paracrine roles of adipokines. Mol Cell Endocrinol 318(1-2), 69-78
  7. Kuda, O., Jelenik, T., Jilkova, Z., Flachs, P., Rossmeisl, M., Hensler, M., Kazdova, L., Ogston, N., Baranowski, M., Gorski, J., Janovska, P., Kus, V., Polak, J., Mohamed-Ali, V., Burcelin, R., Cinti, S., Bryhn, M., Kopecky, J. (2009). n-3 fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory effects on muscle glycogen synthesis in mice fed a high-fat diet. Diabetologia 52(5), 941-951
  8. Madani, R., Karastergiou, K., Ogston, N. C., Bhome, R., Haloob, N., Tan, G. D., Karpe, F., Malone-Lee, J., Jahangiri, M., Hashemi, M., Mohamed-Ali, V. (2009). RANTES release by human adipose tissue in vivo and evidence for depot specific differences. American Journal of Physiology – Endocrinology and Metabolism 296(6), E1262-E1268
  9. Rossmeisl, M., Jelenik, T., Jilkova, Z., Slamova, K., Kus, V., Hensler, M., Medrikova, D., Povysil, C., Flachs, P., Mohamed-Ali, V., Bryhn, M., Berge, K., Holmeide, A. K., Kopecky, J. (2009). Prevention and reversal of obesity and glucose intolerance in mice by DHA derivatives. Obesity (Silver Spring) 17(5), 1023-1031
  10. Tsilchorozidou, T., Mohamed-Ali, V., Conway, G. S. (2009). Determinants of interleukin-6 and C-reactive protein vary in polycystic ovary syndrome, as do effects of short- and long-term metformin therapy. Horm Res 71(3), 148-154
  11. Ogston, N. C., Karastergiou, K., Hosseinzadeh-Attar, M. J., Bhome, R., Madani, R., Stables, M., Gilroy, D., Flachs, P., Hensler, M., Kopecky, J., Mohamed-Ali, V. (2008). Low dose acetylsalicylic acid inhibits the secretion of interleukin-6 from white adipose tissue. International Journal of Obesity 32, 1807-1815
  12. Flachs, P., Mohamed-Ali, V., Horakova, O., Rossmeisi, M., Hosseinzadeh-Attar, M. J., Hensler, M., Ruzickova, J., Kopecky, J. (2006). Polyunsaturated fatty acids of marine origin induce adiponectin in mice fed high-fat diet. Diabetologia 49(2), 394-397
  13. Brydon, L., Edwards, S., Jia, H., Mohamed-Ali, V., Zachary, I., Martin, J. F., Steptoe, A. (2005). Psychological stress activates interleukin-1β gene expression in human mononuclear cells. Brain, Behavior, and Immunity 19(6), 540-546
  14. Ostberg, J. E., Hosseinzadeh-Attar, M. J., Mohamed-Ali, V., Conway, G. S. (2005). Adipokine dysregulation in Turner Syndrome: comparison of circulating interleukin-6 and leptin concentrations with measures of adiposity and C-reactive protein. Journal of Clinical Endocrinology and Metabolism 90, 2948-2953
  15. Brydon, L., Edwards, S., Mohamed-Ali, V., Steptoe, A. (2004). Socioeconomic status and stress-induced increases in interleukin-6. Brain, Behavior, and Immunity 18(3), 281-290
  16. Clapp, B. R., Hingorani, A. D., Kharbanda, R. K., Mohamed-Ali, V., Stephens, J. W., Vallance, P., MacAllister, R. J. (2004). Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress. Cardiovascular Research 64(1), 172-178
  17. D’Aiuto, F., Nibali, L., Mohamed-Ali, V., Vallance, P., Tonetti, M. S. (2004). Periodontal therapy: a novel non-drug-induced experimental model to study human inflammation. Journal of Periodontal Research 39(5), 294-299
  18. Kelberman, D., Hawe, E., Luong, L. A., Mohamed-Ali, V., Lundman, P., Tornvall, P., Aillaud, M. F., Juhan-Vague, I., Yudkin, J. S., Margaglione, M., di Minno, G., Tremoli, E., Humphries SE HIFMECH study, G. R. O. U. P. (2004). Effect of Interleukin-6 promoter polymorphisms in survivors of myocardial infarction and matched controls in the North and South of Europe. The HIFMECH Study. Thrombosis and Haemostasis 92(5), 1122-1128
  19. Yudkin, J. S., Juhan-Vague, I., Hawe, E., Humphries, S. E., di Minno, G., Margaglione, M., Tremoli, E., Kooistra, T., Morange, P. E., Lundman, P., Mohamed-Ali, V., Hamsten A The HIFMECH Study, G. R. O. U. P. (2004). Low-grade inflammation may play a role in the etiology of the metabolic syndrome in patients with coronary heart disease: the HIFMECH study. Metabolism 53(7), 852-857
  20. Flower, L., Gray, R., Pinkney, J., Mohamed-Ali, V. (2003). Stimulation of interleukin-6 release by interleukin-1beta from isolated human adipocytes. Cytokine 21(1), 32-37
  21. Kunz-Ebrecht, S. R., Mohamed-Ali, V., Feldman, P. J., Kirschbaum, C., Steptoe, A. (2003). Cortisol responses to mild psychological stress are inversely associated with proinflammatory cytokines. Brain, Behavior, and Immunity 17(5), 373-383
  22. Owen, N., Poulton, T., Hay, F. C., Mohamed-Ali, V., Steptoe, A. (2003). Socioeconomic status, C-reactive protein, immune factors, and responses to acute mental stress. Brain, Behavior, and Immunity 17(4), 286-295
  23. Paisley, K. E., Beaman, M., Tooke, J. E., Mohamed-Ali, V., Lowe, G. D., Shore, A. C. (2003). Endothelial dysfunction and inflammation in asymptomatic proteinuria. Kidney International 63(2), 624-633
  24. Panahloo, A., Mohamed-Ali, V., Gray, R. P., Humphries, S. E., Yudkin, J. S. (2003). PAI-1 activity post myocardial infarction: the role of acute phase reactants, insulin-like molecules and promoter (4G/5G) polymorphism in the PAI-1 gene. Atherosclerosis 168, 297-304
  25. Crown, A. L., Cottle, K., Lightman, S. L., Falk, S., Mohamed-Ali, V., Armstrong, L., Millar, A. B., Holly, J. M. (2002). What is the role of the insulin-like growth factor system in the pathophysiology of cancer cachexia, and how is it regulated? Clin Endocrinol (Oxf) 56(6), 723-733
  26. Mohamed-Ali, V., Pinkney, J. (2002). Therapeutic potential of insulin-like growth factor-1 in patients with diabetes mellitus. Treat Endocrinology 1(6), 399-410
  27. Steptoe, A., Owen, N., Kunz, S., Mohamed-Ali, V. (2002). Inflammatory cytokines, socioeconomic status, and acute stress responsivity. Brain, Behavior, and Immunity 16, 774-784
  28. Mohamed-Ali, V., Armstrong, L., Clarke, D., Bolton, C. H., Pinkney, J. H. (2001). Evidence for the regulation of levels of plasma adhesion molecules by proinflammatory cytokines and their soluble receptors in type 1 diabetes. Journal of Internal Medicine 250(5), 415-421
  29. Mohamed-Ali, V., Flower, L., Sethi, J., Hotamisligil, G., Gray, R., Humphries, S. E., York, D. A., Pinkney, J. (2001). beta-Adrenergic regulation of IL-6 release from adipose tissue: in vivo and in vitro studies. Journal of Clinical Endocrinology and Metabolism 86(12), 5864-5869
  30. Steptoe, A., Owen, N., Willemsen, G., Mohamed-Ali, V. (2001). Inflammatory cytokine responses are associated with individual differences in cardiovascular stress reactions. Psychosom med 63(1), 115-116
  31. Steptoe, A., Willemsen, G., Owen, N., Flower, L., Mohamed-Ali, V. (2001). Acute mental stress elicits delayed increases in circulating inflammatory cytokine levels. Clinical Science 101(2), 185-192
  32. Flower, L., Ahuja, R. H., Humphries, S. E., Mohamed-Ali, V. (2000). Effects of sample handling on the stability of interleukin 6, tumour necrosis factor-alpha and leptin. Cytokine 12(11), 1712-1716
  33. Pinkney, J. H., Boss, O., Bray, G. A., Bulmer, K., Coppack, S. W., Mohamed-Ali, V. (2000). Physiological relationships of uncoupling protein-2 gene expression in human adipose tissue in vivo. Journal of Clinical Endocrinology and Metabolism 85, 2312-2317
  34. Pinkney, J. H., Goodrick, S. J., Katz, J. R., Johnson, A. B., Lightman, S. L., Coppack, S. W., Medbak, S., Mohamed-Ali, V. (2000). Thyroid and sympathetic influences on plasma leptin in hypothyroidism and hyperthyroidism. Int J Obes Relat Metab Disord 24 Suppl 2, S165-S166
  35. Yudkin, J. S., Kumari, M., Humphries, S. E., Mohamed-Ali, V. (2000). Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link? Atherosclerosis 148(2), 209-214
  36. Yudkin, J. S., Panahloo, A., Stehouwer, C., Emeis, J. J., Bulmer, K., Mohamed-Ali, V., Denver, A., E, (2000). The influence of improved glycaemic control with insulin and sulphonylureas on acute phase and endothelial markers in Type II diabetic subjects. Diabetologia 43, 1099-1106
  37. Humphries, S. E., Luong, L. A., Montgomery, H. E., Day, I. N., Mohamed Ali, V., Yudkin, J. S. (1999). Gene-environment interaction in the determination of levels of plasma fibrinogen. Thrombosis and Haemostasis 82(2), 818-825
  38. Katz, J. R., Mohamed-Ali, V., Wood, P. J., Yudkin, J. S., Coppack, S. W. (1999). An in vivo study of the cortisol-cortisone shuttle in subcutaneous abdominal adipose tissue. Clin Endocrinol (Oxf) 50(1), 63-68
  39. Mohamed-Ali, V., Goodrick, S., Bulmer, K., Holly, J. M., Yudkin, J. S., Coppack, S. W. (1999). Production of soluble tumor necrosis factor receptors by human subcutaneous adipose tissue in vivo. Am J Physiol 277(6 Pt 1), E971-E975
  40. Mohamed-Ali, V., Pinkney, J. H., Panahloo, A., Cwyfan-Hughes, S., Holly, J. M., Yudkin, J. S. (1999). Insulin-like growth factor binding protein-1 in NIDDM: relationship with the insulin resistance syndrome. Clin Endocrinol (Oxf) 50(2), 221-228
  41. Yudkin, J. S., Coppack, S. W., Bulmer, K., Rawesh, A., Mohamed-Ali, V. (1999). Lack of evidence for secretion of plasminogen activator inhibitor-1 by human subcutaneous adipose tissue in vivo. Thrombosis Research 96(1), 1-9
  42. Yudkin, J. S., Yajnik, C. S., Mohamed-Ali, V., Bulmer, K. (1999). High levels of circulating proinflammatory cytokines and leptin in urban, but not rural, Indians. A potential explanation for increased risk of diabetes and coronary heart disease. Diabetes Care 22(2), 363-364
  43. Britton, M. E., Denver, A. E., Mohamed-Ali, V., Yudkin, J. S. (1998). Effects of Glimepiride vs Glibenclamide on Ischaemic Heart Disease Risk Factors and Glycaemic Control in Patients with Type 2 Diabetes Mellitus. Clin Drug Investig 16(4), 303-317
  44. Coppack, S. W., Pinkney, J. H., Mohamed-Ali, V. (1998). Leptin production in human adipose tissue. Proc Nutr Soc 57(3), 461-470
  45. Fishman, D., Faulds, G., Jeffery, R., Mohamed-Ali, V., Yudkin, J. S., Humphries, S., Woo, P. (1998). The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 102(7), 1369-1376
  46. Mohamed-Ali, V., Pinkney, J. H., Coppack, S. W. (1998). Adipose tissue as an endocrine and paracrine organ. Int J Obes Relat Metab Disord 22(12), 1145-1158
  47. Nagi, D. K., Foy, C. A., Mohamed-Ali, V., Yudkin, J. S., Grant, P. J., Knowler, W. C. (1998). Angiotensin-1-converting enzyme (ACE) gene polymorphism, plasma ACE levels, and their association with the metabolic syndrome and electrocardiographic coronary artery disease in Pima Indians. Metabolism 47(5), 622-626
  48. Nagi, D. K., Knowler, W. C., Mohamed-Ali, V., Bennett, P. H., Yudkin, J. S. (1998). Intact proinsulin, des 31,32 proinsulin, and specific insulin concentrations among nondiabetic and diabetic subjects in populations at varying risk of type 2 diabetes. Diabetes Care 21(1), 127-133
  49. Ogilvy-Stuart, A. L., Hands, S. J., Adcock, C. J., Holly, J. M., Matthews, D. R., Mohamed-Ali, V., Yudkin, J. S., Wilkinson, A. R., Dunger, D. B. (1998). Insulin, insulin-like growth factor I (IGF-I), IGF-binding protein-1, growth hormone, and feeding in the newborn. J Clin Endocrinol Metab 83(10), 3550-3557
  50. Panahloo, A., Mohamed-Ali, V., Andrés, C., Denver, A. E., Yudkin, J. S. (1998). Effect of insulin versus sulfonylurea therapy on cardiovascular risk factors and fibrinolysis in type II diabetes. Metabolism 47(6), 637-643
  51. Pinkney, J. H., Coppack, S. W., Mohamed-Ali, V. (1998). Effect of isoprenaline on plasma leptin and lipolysis in humans. Clin Endocrinol (Oxf) 48(4), 407-411
  52. Pinkney, J. H., Goodrick, S. J., Katz, J., Johnson, A. B., Lightman, S. L., Coppack, S. W., Mohamed-Ali, V. (1998). Leptin and the pituitary-thyroid axis: a comparative study in lean, obese, hypothyroid and hyperthyroid subjects. Clin Endocrinol (Oxf) 49(5), 583-588
  53. Savage, M. W., Mohamed-Ali, V., Williams, G. (1998). Suppression of post-glucose hyperinsulinaemia does not affect blood pressure in either normotensive or hypertensive subjects. Clin Sci (Lond) 94(6), 609-614
  54. Gray, R. P., Panahloo, A., Mohamed-Ali, V., Patterson, D. L., Yudkin, J. S. (1997). Proinsulin-like molecules and plasminogen activator inhibitor type 1 (PAI-1) activity in diabetic and non-diabetic subjects with and without myocardial infarction. Atherosclerosis 130(1-2), 171-178
  55. Mohamed-Ali, V., Goodrick, S., Rawesh, A., Katz, D. R., Miles, J. M., Yudkin, J. S., Klein, S., Coppack, S. W. (1997). Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo. J Clin Endocrinol Metab 82(12), 4196-4200
  56. Mohamed-Ali, V., Pinkney, J. H., Panahloo, A., Goodrick, S., Coppack, S. W., Yudkin, J. S. (1997). Relationships between plasma leptin and insulin concentrations, but not insulin resistance, in non-insulin-dependent (type 2) diabetes mellitus. Diabet Med 14(5), 376-380
  57. Nagi, D. K., McCormack, L. J., Mohamed-Ali, V., Yudkin, J. S., Knowler, W. C., Grant, P. J. (1997). Diabetic retinopathy, promoter (4G/5G) polymorphism of PAI-1 gene, and PAI-1 activity in Pima Indians with type 2 diabetes. Diabetes Care 20(8), 1304-1309
  58. Yudkin, J. S., Andres, C., Mohamed, A., Gould, M., Panahloo, A., Haines, A. P., Humphries, S., Talmud, P. (1997). The angiotensin-converting enzyme gene and the angiotensin II type I receptor gene as candidate genes for microalbuminuria. A study in nondiabetic and non-insulin-dependent diabetic subjects. Arterioscler thromb vasc biol 17(10), 2188-2191
  59. Yudkin, J. S., Denver, A. E., Mohamed-Ali, V., Ramaiya, K. L., Nagi, D. K., Goubet, S., McLarty, D. G., Swai, A. (1997). The relationship of concentrations of insulin and proinsulin-like molecules with coronary heart disease prevalence and incidence. A study of two ethnic groups. Diabetes Care 20(7), 1093-1100
  60. Klein, S., Coppack, S. W., Mohamed-Ali, V., Landt, M. (1996). Adipose tissue leptin production and plasma leptin kinetics in humans. Diabetes 45(7), 984-987
  61. McCormack, L. J., Nagi, D. K., Stickland, M. H., Mansfield, M. W., Mohamed-Ali, V., Yudkin, J. S., Knowler, W. C., Grant, P. J. (1996). Promoter (4G/5G) plasminogen activator inhibitor-1 genotype in Pima Indians: relationship to plasminogen activator inhibitor-1 levels and features of the insulin resistance syndrome. Diabetologia 39(12), 1512-1518
  62. Mohamed-Ali, V., Nagi, D. K., Yudkin, J. S. (1996). Simple, sensitive microplate IRMAs for intact and des-31,32-proinsulin compared with HPLC and cellulose IRMAs. Clinical Chemistry 42(6), 977-979
  63. Nagi, D. K., Mohamed Ali, V., Jain, S. K., Walji, S., Yudkin, J. S. (1996). Plasminogen activator inhibitor (PAI-1) activity is elevated in Asian and Caucasian subjects with non-insulin-dependent (type 2) diabetes but not in those with impaired glucose tolerance (IGT) or non-diabetic Asians. Diabet Med 13(1), 59-64.
  64. Pappas, S., Donohue, S. M., Denver, A. E., Mohamed-Ali, V., Goubet, S., Yudkin, J. S. (1996). Glucose intolerance in thalassemia major is related to insulin resistance and hepatic dysfunction. Metabolism 45(5), 652-657.
  65. Carstensen, E., Ramaiya, K., Denver, E., Mohamed-Ali, V., Yudkin, J. S. (1995). The contribution of the sympathoadrenomedullary system to the etiology of essential hypertension: a study using plasma and platelet catecholamine concentrations. Journal of Clinical Endocrinology and Metabolism 80(2), 455-460.
  66. Gray, R. P., Mohamed-Ali, V., Patterson, D. L., Yudkin, J. S. (1995). Determinants of plasminogen activator inhibitor-1 activity in survivors of myocardial infarction. Thrombosis and Haemostasis 73(2), 261-267.
  67. Kruszynska, Y. T., Harry, D. S., Mohamed-Ali, V., Home, P. D., Yudkin, J. S., McIntyre, N. (1995). The contribution of proinsulin and des-31,32 proinsulin to the hyperinsulinemia of diabetic and nondiabetic cirrhotic patients. Metabolism 44(2), 254-260.
  68. Mohamed-Ali, V., Gould, M. M., Gillies, S., Goubet, S., Yudkin, J. S., Haines, A. P. (1995). Association of proinsulin-like molecules with lipids and fibrinogen in non-diabetic subjects–evidence against a modulating role for insulin. Diabetologia 38(9), 1110-1116.
  69. Panahloo, A., Andres, C., Mohamed-Ali, V., Gould, M. M., Talmud, P., Humphries, S. E., Yudkin, J. S. (1995). The insertion allele of the ACE gene I/D polymorphism. A candidate gene for insulin resistance? Circulation 92(12), 3390-3393.
  70. Panahloo, A., Mohamed-Ali, V., Lane, A., Green, F., Humphries, S. E., Yudkin, J. S. (1995). Determinants of plasminogen activator inhibitor 1 activity in treated NIDDM and its relation to a polymorphism in the plasminogen activator inhibitor 1 gene. Diabetes 44(1), 37-42.
  71. Pinkney, J. H., Denver, A. E., Mohamed-Ali, V., Foster, C., Yudkin, J. S. (1995). Insulin resistance in non-insulin-dependent diabetes mellitus is associated with microalbuminuria independently of ambulatory blood pressure. Journal of Diabetes and its Complications 9(4), 230-233.
  72. Pinkney, J. H., Foyle, W. J., Denver, A. E., Mohamed-Ali, V., McKinlay, S., Yudkin, J. S. (1995). The relationship of urinary albumin excretion rate to ambulatory blood pressure and erythrocyte sodium-lithium countertransport in NIDDM. Diabetologia 38(3), 356-362.
  73. Gould, M. M., Mohamed-Ali, V., Goubet, S. A., Yudkin, J. S., Haines, A. P. (1994). Associations of urinary albumin excretion rate with vascular disease in europid nondiabetic subjects. Journal of Diabetes and its Complications 8(3), 180-188.
  74. Pinkney, J. H., Mohamed-Ali, V., Denver, A. E., Foster, C., Sampson, M. J., Yudkin, J. S. (1994). Insulin resistance, insulin, proinsulin, and ambulatory blood pressure in type II diabetes. Hypertension 24(3), 362-367.
  75. Gould, M. M., Mohamed-Ali, V., Goubet, S. A., Yudkin, J. S., Haines, A. P. (1993). Microalbuminuria: associations with height and sex in non-diabetic subjects. BMJ (Clinical Research Ed.) 306(6872), 240-242.

Book Chapters

  1. Madani R, Ogston NC, Mohamed-Ali-V, (2009). Frühbeck, G. (Ed.). In Peptides in Energy Balance and Obesity ( pp.195-228). Cabi.
  2. Clarke-DK, Mohamed-Ali V. (2005). Kumar, S., O’Rahilly, S. (Eds.). In Insulin resistance ( pp.269-297). Wiley.
  3. Mohamed-Ali V, Coppack SW. (2005). Frayn, K. N., Stanner, S., Foundation, B. N. (Eds.). In Cardiovascular disease. Wiley-Blackwell.


Sayed Goda

  1. Goda SK, Elsayed IE, Khodair TA, El-Sayed W, Mohamed ME. Screening for and isolation and identification of malathion-degrading bacteria: cloning and sequencing a gene that potentially encodes the malathion-degrading enzyme, carboxylestrase in soil bacteria. Biodegradation. 2010 ;21:903-13.
  2. Goda SK, Abu Aqel YW, Al-Aswad MR, Rashedy FA, Mohamed AS. Production of synthetic methionine-free and synthetic methionine-limited alpha casein: protein foodstuff for patients with homocystinuria due to cystathionine beta-synthase deficiency. Protein J. 2010 ;29:44-9.
  3. Goda SK, Rashidi FA, Fakharo AA, Al-Obaidli A. Functional overexpression and purification of a codon optimized synthetic glucarpidase (carboxypeptidase G2) in Escherichia coli. Protein J. 2009 Dec;28(9-10):435-42.
  4. Papageorgiou AC, Baker MD, McLeod JD, Goda SK, Manzotti CN, Sansom DM, Tranter HS, Acharya KR. Identification of a secondary zinc-binding site in staphylococcal enterotoxin C2. Implications for superantigen recognition. J Biol Chem. 2004 ;279:1297-303.
  5. Goda SK, Sharman AF, Yates M, Mann N, Carr N, Minton NP, Brehm JK. Recombinant expression analysis of natural and synthetic bovine alpha-casein in Escherichia coli. Appl Microbiol Biotechnol. 2000;54:671-6.
  6. Goda SK, Eisa O, Akhter M, Minton NP. Molecular analysis of the malR gene of Clostridium butyricum NCIMB 7423, a member of the LacI-GalR family of repressor proteins. FEMS Microbiol Lett. 1998;165:193-200.
  7. Goda SK, Eissa O, Akhtar M, Minton NP. Molecular analysis of a Clostridium butyricum NCIMB 7423 gene encoding 4-alpha-glucanotransferase and characterization of the recombinant enzyme produced in Escherichia coli. Microbiology. 1997 ;143:3287-94.
  8. Goda SK, Minton NP. A simple procedure for gel electrophoresis and northern blotting of RNA. Nucleic Acids Res. 1995 Aug 25;23(16):3357-8.
  9. Goda SK, Minton NP, Botting NP, Gani D. Cloning, sequencing, and expression in Escherichia coli of the Clostridium tetanomorphum gene encoding beta-methylaspartase and characterization of the recombinant protein. Biochemistry. 1992 Nov 10;31(44):10747-56.
  10. Goda SK, Akhtar M. Neomycin biosynthesis: the incorporation of D-6-deoxy-glucose derivatives and variously labelled glucose into the 2-deoxystreptamine ring. Postulated involvement of 2-deoxyinosose synthase in the biosynthesis. J Antibiot (Tokyo). 1992;45:984-94.


Nelson Orie

  1. Orie NN, Ledwozyw A, Williams DJ, Whittle BJ, Clapp LH. Differential actions of the prostacyclin analogues treprostinil and iloprost and the selexipag metabolite, MRE-269 (ACT-333679) in rat small pulmonary arteries and veins. Prostaglandins and Other Lipid Mediators (Accepted. 2013)
  2. Chan YL, Orie NN, Dyson A, Taylor V, Stidwill RP, Clapp LH, Singer M. Inhibition of vascular adenosine triphosphate-sensitive potassium channels by sympathetic tone during sepsis. Crit Care Med. 2012 Apr;40(4):1261-8.
  3. O’Brien AJ, Terala D, Orie NN, Davies NA, Zolfaghari P, Singer M, Clapp LH. BK large conductance Ca²+-activated K+ channel-deficient mice are not resistant to hypotension and display reduced survival benefit following polymicrobial sepsis. Shock. 2011; 35:485-91.
  4. Orie NN, Clapp LH. Role of prostanoid IP and EP receptors in mediating vasorelaxant responses to PGI2 analogues in rat tail artery: Evidence for Gi/o modulation via EP3 receptors. Eur J Pharmacol. 2011 Mar 11;654(3):258-65.
  5. Orie NN, Thomas AM, Perrino BA, Tinker A, Clapp LH. Ca2+/calcineurin regulation of cloned vascular K ATP channels: crosstalk with the protein kinase A pathway. Br J Pharmacol. 2009 ;157:554-64..
  6. Barrett LK, Orie NN, Taylor V, Stidwill RP, Clapp LH, Singer M. Differential effects of vasopressin and norepinephrine on vascular reactivity in a long-term rodent model of sepsis. Crit Care Med. 2007 ;35:2337-43.
  7. Clapp LH, Orie NN. Stoking up BKCa channels in hemorrhagic shock: which channel subunit is really fueling the fire? Circ Res. 2007;101:436-8.
  8. Orie NN, Fry CH, Clapp LH. Evidence that inward rectifier K+ channels mediate relaxation by the PGI2 receptor agonist cicaprost via a cyclic AMP-independent mechanism. Cardiovasc Res. 2006 Jan;69(1):107-15.
  9. Orie NN, Vallance P, Jones DP, Moore KP. S-nitroso-albumin carries a thiol-labile pool of nitric oxide, which causes venodilation in the rat. Am J Physiol Heart Circ Physiol. 2005;289:H916-23.
  10. Mani AR, Pannala AS, Orie NN, Ollosson R, Harry D, Rice-Evans CA, Moore KP. Nitration of endogenous para-hydroxyphenylacetic acid and the metabolism of nitrotyrosine. Biochem J. 2003 ;374:521-7.
  11. Orie NN, Zidek W, Tepel M. Increased intracellular generation of reactive oxygen species in mononuclear leukocytes from patients with diabetes mellitus type 2. Exp Clin Endocrinol Diabetes. 2000;108(3):175-80.
  12. Tepel M, Echelmeyer M, Orie NN, Zidek W. Increased intracellular reactive oxygen species in patients with end-stage renal failure: effect of hemodialysis. Kidney Int. 2000 Aug;58(2):867-72.
  13. Orie NN, Zidek W, Tepel M. Reactive oxygen species in essential hypertension and non-insulin-dependent diabetes mellitus. Am J Hypertens. 1999 Dec;12(12 Pt 1-2):1169-74.
  14. Orie NN, Zidek W, Tepel M. Tyrosine and calcium/calmodulin kinases are common signaling components in the generation of reactive oxygen species in human lymphocytes. Life Sci. 1999;65(20):2135-42.
  15. Orie NN. Comparison of normal respiratory function values in young Kenyans with those of other Africans and Caucasians.East Afr Med J. 1999 Jan;76(1):31-4.
  16. Orie NN, Zidek W, Tepel M. Chemoattractant- and mitogen-induced generation of reactive oxygen species in human lymphocytes: the role of calcium. Exp Physiol. 1999 May;84(3):515-20.
  17. Orie NN, Anyaegbu NO. Nifedipine effectively lowers salt-induced high blood pressure in diabetic rats. Gen Pharmacol. 1999 Apr;32(4):471-4.
  18. Orie NN, Osirim FE. Insulin therapy could prevent salt-induced high blood pressure in diabetes mellitus.East Afr Med J. 1997 Sep;74(9):579-81.
  19. Orie NN. Direct vascular effects of plantain extract in rats. Exp Physiol. 1997 May;82(3):501-6.
  20. Owu DU, Orie NN, Osim EE. Altered responses of isolated aortic smooth muscle following chronic ingestion of palm oil diets in rats. Afr J Med Med Sci. 1997 Mar-Jun;26(1-2):83-6.
  21. Orie NN, Aloamaka CP, Iyawe VI. Enhanced sensitivity to salt-induced high blood pressure in diabetes mellitus. Res Exp Med (Berl). 1994;194(3):197-202.
  22. Orie NN, Aloamaka CP, Antai AB.Enhanced Na-K ATPase activity in the aorta may explain the unaltered contractile responses to KCl in diabetes mellitus.Indian J Physiol Pharmacol. 1993 Jul;37(3):199-203.
  23. Orie NN, Aloamaka CP, Iyawe VI.Duration-dependent attenuation of acetylcholine–but not histamine–induced relaxation of the aorta in diabetes mellitus.Gen Pharmacol. 1993 Mar;24(2):329-32.
  24. Orie NN, Ekon EU. The bronchodilator effect of Garcinia Kola. East Afr Med J. 1993 Mar;70(3):143-5.
  25. Orie NN, Aloamaka CP. Diabetic rat aorta responsiveness to D600 and nifedipine. Clin Exp Pharmacol Physiol. 1993 Feb;20(2):77-81.
  26. Orie NN, Aloamaka CP. Duration-dependent variability in the responses of diabetic rat aorta to noradrenaline and 5-hydroxytryptamine.Gen Pharmacol. 1993 Jan;24(1):243-6.
  27. Orie NN, Ibanga IN. The effect of nocotiana tabacum (snuff) on blood pressure and pulse rate of Nigerians. East Afr Med J. 1992 Sep;69(9):535-8.


Mohamed ElRayess

  1. Gomma AH, Elrayess MA, Knight CJ, Hawe E, Fox KM, Humphries SE. The endothelial nitric oxide synthase (Glu298Asp and -786T>C) gene polymorphisms are associated with coronary in-stent restenosis. Eur Heart J. 2002 Dec;23(24):1955-62.
  2. Mohamed A. Elrayess, Karen E. Webb, David M. Flavell, Mikko Syvänne, Marja-Riitta Taskinen, M. Heikki Frick, Markku S. Nieminen, Y. Antero Kesäniemi, Amos Pasternack, J. Wouter Jukema, John JP. Kastelein, Aeilko H. Zwinderman, and Steve E. Humphries. A novel functional polymorphism in the PECAM-1 gene (53G>A) is associated with progression of atherosclerosis in the LOCAT and REGRESS studies. Atherosclerosis. 2003 May;168(1):131-8.
  3. M A Elrayess, K E Webb, GJ Bellingan, M Syvänne, M R Taskinen, M H Frick, M S Nieminen, Y A Kesäniemi, A Pasternack, and S E Humphries. R670G polymorphism in the PECAM-1 gene alters PECAM-1 phosphorylation and is associated with coronary artery disease. Atherosclerosis. 2004 Nov;177(1):127-35.
  4. Elrayess MA, Talmud PJ. Platelet endothelial cell adhesion molecule-1 (PECAM-1) & coronary heart disease. Indian J Med Res. 2005 Feb;121(2):77-9. No abstract available.
  5. Li P, Elrayess MA, Gomma AH, Palmen J, Hawe E, Fox KM, Humphries SE. The microsatellite polymorphism of HO-1 is associated with baseline plasma IL-6 level but not with restenosis after coronary in-stenting. Chin Med J (Engl). 2005 Sep 20;118(18):1525-32.
  6. Urquhart DS, Allen J, Elrayess M, Fidler K, Klein N, Jaffe A. Modifier effect of the Toll-like receptor 4 D299G polymorphism in children with cystic fibrosis. Arch Immunol Ther Exp (Warsz). 2006 Jul-Aug;54(4):271-6.


Bioanalysis 2012 Georgakopoulos
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Bioanalysis 2012 Friedmann
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Georgakopoulos Review
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